Antimicrobial Peptides from Human Platelets

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Antimicrobial peptides from human platelets.

Platelets share structural and functional similarities with granulocytes known to participate in antimicrobial host defense. To evaluate the potential antimicrobial activities of platelet proteins, normal human platelets were stimulated with human thrombin in vitro. Components of the stimulated-platelet supernatants were purified to homogeneity by reversed-phase high-performance liquid chromato...

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ژورنال

عنوان ژورنال: Infection and Immunity

سال: 2002

ISSN: 0019-9567,1098-5522

DOI: 10.1128/iai.70.12.6524-6533.2002